Table 5 Precision data of the Fosamprenavir and its impurities
Precision | Amino impurity | Propyl impurity | Isomer impurity | Fosamprenavir | Nitro impurity | Amprenavir impurity | |
|---|---|---|---|---|---|---|---|
System precision | *Mean peak area | 21599.8 | 21,453 | 34580.4 | 13403.60 | 7977.8 | 41944.20 |
SD | 107.26 | 390.75 | 104.54 | 108.49 | 398.46 | 121.63 | |
%RSD | 0.50 | 1.13 | 0.78 | 1.36 | 0.95 | 0.29 | |
Method precision | *Mean % recovery | 100 | 98.2 | 98.6 | 100.06 | 99.68 | 100.68 |
SD | 0.80 | 1.17 | 1.57 | 1.01 | 0.86 | 1.32 | |
%RSD | 0.80 | 1.20 | 1.60 | 1.01 | 0.87 | 1.32 | |